OK, I'm no expert, but, if it's cold I wear a pair of thermals under normal khakis. If the temperatures are normal (50's or higher) I'll just wear the khakis. Is moisture a problem? Not really. A few beads of sweat will form, and, in cold water, you will feel an occasional pinpoint of cold on your legs from time to time (as in 1 every 30 minutes), but once you realize what it is, it's not a problem. When I take my waders off, I do not have wet spots on my legs, and I have been comfortable all day.